Studies suggest that CBD may provide relief for pain and inflammation. There's also evidence that topical CBD products, like creams, can help with a variety of pain sensations, including: Arthritis-related pain. CBD topicals here can be applied directly to the troubling area, giving a soothing effect to the skin and sore muscles. These CBD topical products are super easy to use and have a long-lasting effect for over 8 to 12 hours.